PROOF PLEASE: The Science Behind The Patch

THE PATCH DIFFERENCE.

Transdermal delivery isn't new. It's been used in medicine for over 45 years, from pain relief to nicotine patches. We just applied it to plant-powered wellness.
Why Most Supplements Fail

YOUR BODY LOSES UP TO 90% BEFORE IT WORKS.

When you swallow a pill, it goes on a journey: stomach acid breaks it down, your intestines try to absorb what's left, then your liver filters most of it out.

This is called the "first-pass effect" — and it's why so many supplements don't deliver what they promise.
  • Only 10-20%

    of oral supplements reach your bloodstream

  • Stomach issues

    nausea, bloating, discomfort

  • Hours to absorb

    before you feel anything

The Science Behind Transdermal Delivery

SKIPS THE STOMACH

Goes straight through your skin into your bloodstream. No digestion. No detours.

STEADY ALL DAY

Slow, controlled release over 8 hours. No spikes. No crashes. Just consistent support.

MORE GETS THROUGH

No first-pass metabolism. Your body actually gets what's on the patch.

EASY ON YOUR SYSTEM

No stomach issues. No food timing. No interference with your morning coffee.

PREDICTABLE RESULTS

Your skin absorbs the same way every time. Less guesswork, more consistency.

TRUSTED SCIENCE

The same delivery method used in pain relief, nicotine, and hormone patches since 1979.

THE DIFFERENCE IS CLEAR.

Patch
Absorption
Up to 90%
Delivery
Direct through skin
First-Pass Effect
Bypassed completely
Release
Steady over 8 hours
Side Effects
None
Convenience
Stick on & forget
Pills
Absorption
Only 10-20%
Delivery
Stomach → Liver → Blood
First-Pass Effect
Reduces effectiveness
Release
Peaks & crashes
Side Effects
Nausea, bloating
Convenience
Timing, food, water
45+ Years of Proof

THE SAME METHOD DOCTORS TRUST.

Transdermal delivery isn't experimental. It's the same proven technology behind:

  • Nicotine patches — helping millions quit smoking since 1984
  • Hormone patches — trusted for hormone replacement therapy
  • Pain relief patches — delivering consistent relief for chronic pain
  • Motion sickness patches — the first FDA-approved patch in 1979

We didn't invent transdermal delivery. We just made it work for plant-powered wellness.

BACKED BY SCIENCE. NOT HYPE.

What peer-reviewed research says about transdermal delivery.

Bypasses First-Pass Metabolism

"Transdermal drug delivery bypasses the gastrointestinal tract and avoids first-pass metabolism. This method is particularly effective for drugs that are poorly absorbed orally."

NCBI StatPearls →
Improved Bioavailability

"Transdermal drug delivery has the advantage of maintaining constant drug plasma levels. Compared to the oral route, losses in bioavailability due to first-pass liver metabolism are reduced."

PubMed →
Fewer Side Effects

"Transdermal drug administration avoids gastrointestinal absorption, minimizes adverse effects arising from peak plasma drug concentrations and improves patient compliance."

PubMed →
Avoids GI Degradation

"Avoids first-pass hepatic metabolism and enzymatic degradation in the gastrointestinal tract. The drug release can be stopped at any time by removing the patch."

PMC →

All sources are peer-reviewed publications from the National Library of Medicine.

10,000+ CUSTOMERS MADE THE SWITCH.

I was skeptical at first, but after two weeks I actually felt different. The cravings are way down. Now I'm on my third order.

Susan M., 54

I've recommended this to everyone. My sister, my coworker, even my mom. We're all hooked.

Author name

No pills, no powders, no hassle. Just stick it on in the morning and forget about it. So simple.

Michelle R., 48

I'm not chasing 30 again. I just want to feel like myself. More energy, better sleep, clearer head. This does that.

Karen T., 51

My wife got me into this. Wasn't expecting much, but the late night cravings are actually gone. No more raiding the fridge at 10pm.

Mike R., 53

SO EASY: 8 SECONDS. THAT'S ALL IT TAKES.

PEEL

Remove patch from the sheet.

STICK

Apply to clean, dry skin on your upper arm, shoulder, or hip.

FORGET

Wear for 8 hours. Go about your day. That's it.

READY TO TRY IT YOURSELF?

Berberine Patch

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Berberine Patch

$29.95
$29.95
(1056 reviews)
NAD+ Cell Renewal Patches

NAD+

NAD+ Cell Renewal Patches

$29.95
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Each patch delivers steady support for 8 hours. Most customers apply one in the morning and remove it before bed.

Apply to clean, dry, hair-free skin. Best spots: upper arm, shoulder, lower back, or hip. Rotate locations daily.

Our patches are designed for sensitive skin. If you experience irritation, try a different location. Redness typically fades within an hour of removal.

Oral supplements lose up to 90% effectiveness through digestion. Our patches deliver directly through your skin, bypassing the gut entirely.

Yes, it's been FDA-approved since 1979 and is used in nicotine patches, hormone therapy, and pain relief. We apply the same science to plant-based wellness.

YOUR SIMPLEST WELLNESS ROUTINE STARTS HERE.

One patch. Once a day. That's it.

SHOP ALL PATCHES

Sources & References

Jeong WY et al. "Recent advances in transdermal drug delivery systems." Biomaterials Research, 2021.

Wong WF et al. "Recent Advancement of Medical Patch for Transdermal Drug Delivery." Medicina, 2023.

Pastore MN et al. "Transdermal patches: history, development and pharmacology." British Journal of Pharmacology, 2015.

StatPearls. "Transdermal Medications." National Library of Medicine, 2024.

Farage MA et al. "Use of transdermal drug formulations in the elderly." PubMed, 2008.

Brown L, Langer R. "Transdermal delivery of drugs." Annual Review of Medicine, 1988.

PMC. "How physical techniques improve transdermal permeation." National Library of Medicine, 2022.